Kate Walsh

By the mid-'90s, Walsh began slowly but surely making the transition to the screen with appearances on TV shows like Homicide: Life on the Street and Law & Order. Walsh's list of film and TV appearances soon grew, and among her scads of roles were a number of prominent parts on very popular shows. She became a regular on The Drew Carey Show in 1997, donning a fat suit to play Drew's weight-struggling girlfriend, and in 2001, she took a recurring role on the HBO series The Mind of the Married Man.

In 2005, Walsh joined the cast of the smash-hit series Grey's Anatomy, playing Dr. Addison Montgomery-Shepherd, estranged (and eventually ex-) wife of "Doctor McDreamy," Patrick Dempsey. Walsh suddenly went from a working actress to a well-known face, and it looked like the perfect time for the actress to segue into the big screen in a starring capacity, after a string of minor appearances in major films. ~ Cammila Albertson, All Movie Guide