A planned romantic rendezvous for Meredith (
Ellen Pompeo) and Derek (
Patrick Dempsey) is interrupted by a train wreck which brings dozens of victims into Seattle Grace. Among these are a twentyish woman named Bonnie (
Monica Keena) and a middle-aged man named Tom (
Bruce A. Young), who form an unusual bond while impaled together on a pole. Meanwhile, a critical operation is put on hold while Cristina (
Sandra Oh) searches for the patient's missing leg; Addison (
Kate Walsh) and Izzie (
Katherine Heigl) struggle to save the life of a burn victim's unborn child; and Alex (
Justin Chambers) tries to care for his patient Mary (
Juliette Jeffers), despite the obnoxious interpolations of Mary's friend Yvonne (Kym Whitley)--whose ceaseless carping about Alex's medical skills and bedside manner cause him to wonder if he has chosen the right profession after all. ~ Hal Erickson, All Movie Guide